What condition is characterized by blue sclera?

What condition is characterized by blue sclera?

• A. Dentinogenesis Imperfecta
• B. Osteogenesis Imperfecta
• C. Fibrous Dysplasia
• D. Marfan Syndrome

Answer: (B)

The condition characterized by blue sclera is Osteogenesis Imperfecta. This genetic disorder affects collagen production, which is crucial for the strength and integrity of bones and connective tissue. As a result, individuals with Osteogenesis Imperfecta often exhibit features such as fragile bones that fracture easily, and one distinctive feature is the appearance of their sclera, which can take on a bluish tint. This blue color arises because the underlying tissue, which is less dense due to collagen deficiency, allows the underlying choroidal veins to show through. In contrast, Dentinogenesis Imperfecta primarily affects the dentin in teeth and does not typically impact the sclera. Fibrous Dysplasia involves abnormal bone development but does not present with blue sclera, and Marfan Syndrome is associated with connective tissue abnormalities leading to cardiovascular and skeletal issues, but again, does not feature blue sclera as a characteristic symptom.

The condition characterized by blue sclera is Osteogenesis Imperfecta. This genetic disorder affects collagen production, which is crucial for the strength and integrity of bones and connective tissue. As a result, individuals with Osteogenesis Imperfecta often exhibit features such as fragile bones that fracture easily, and one distinctive feature is the appearance of their sclera, which can take on a bluish tint. This blue color arises because the underlying tissue, which is less dense due to collagen deficiency, allows the underlying choroidal veins to show through.

In contrast, Dentinogenesis Imperfecta primarily affects the dentin in teeth and does not typically impact the sclera. Fibrous Dysplasia involves abnormal bone development but does not present with blue sclera, and Marfan Syndrome is associated with connective tissue abnormalities leading to cardiovascular and skeletal issues, but again, does not feature blue sclera as a characteristic symptom.