Which ocular finding is indicative of Dentinogenesis Imperfecta?

Which ocular finding is indicative of Dentinogenesis Imperfecta?

• A. Red sclera
• B. Yellow sclera
• C. Blue sclera
• D. Green sclera

Answer: (C)

Dentinogenesis Imperfecta is a genetic condition affecting the development of dentin, resulting in discolored teeth and various ocular findings. One notable ocular manifestation associated with this condition is the appearance of the sclera. In individuals with Dentinogenesis Imperfecta, the sclera often has a bluish hue, which is attributed to the underlying connective tissue's structure and its effect on light scattering. The blue sclera occurs because the thin sclera allows for the underlying choroidal tissue, which has a darker pigmentation, to be more visible. This can be particularly pronounced in individuals with certain types of collagen disorders, including those that are related to Dentinogenesis Imperfecta. In contrast, other scleral colors, such as red, yellow, or green, do not typically correlate with Dentinogenesis Imperfecta. Red sclera might suggest inflammation or underlying vascular issues, yellow sclera could indicate jaundice or liver issues, and green sclera is not a noted clinical finding for this condition. Thus, the presence of a blue sclera is the characteristic indicative of Dentinogenesis Imperfecta.

Dentinogenesis Imperfecta is a genetic condition affecting the development of dentin, resulting in discolored teeth and various ocular findings. One notable ocular manifestation associated with this condition is the appearance of the sclera. In individuals with Dentinogenesis Imperfecta, the sclera often has a bluish hue, which is attributed to the underlying connective tissue's structure and its effect on light scattering.

The blue sclera occurs because the thin sclera allows for the underlying choroidal tissue, which has a darker pigmentation, to be more visible. This can be particularly pronounced in individuals with certain types of collagen disorders, including those that are related to Dentinogenesis Imperfecta.

In contrast, other scleral colors, such as red, yellow, or green, do not typically correlate with Dentinogenesis Imperfecta. Red sclera might suggest inflammation or underlying vascular issues, yellow sclera could indicate jaundice or liver issues, and green sclera is not a noted clinical finding for this condition. Thus, the presence of a blue sclera is the characteristic indicative of Dentinogenesis Imperfecta.